COVID: Blood clot risk even higher one year after infection, study finds

A new UK study examining the health records of 48 million unimmunized adults, covering almost the entire adult population in the UK and Wales, found that nearly a year after being infected with COVID-19, they developed blood clots. The risk of doing so remained high. Pandemic year.

In a peer-reviewed paper published in the American Heart Association’s Circulation Journal, the researchers found that COVID-19 could cause more than 10,500 additional heart attacks, strokes, and other blood clot-related events in England and Wales in 2020. is assumed to have occurred. Although the excess risk was small overall and declined over time, the researchers found that the likelihood of developing venous thromboembolism (VTE) after a COVID-19 diagnosis remained nearly constant for up to 49 weeks after a positive test. We found that it remained twice as high. A viral infection was not diagnosed.

VTE is a blood clot in a vein, and according to the U.S. Centers for Disease Control and Prevention, it’s a serious, underdiagnosed, but preventable condition that can cause disability and death. A blood clot in the lung is an example of VTE. Arterial thrombosis is a blood clot that forms in an artery and is potentially dangerous.

“While we do believe that risk declines very quickly, especially for heart attack and stroke, the finding that risk remains elevated for some time is an indication of the long-term impact of COVID-19, which we are only beginning to understand. “It highlights a significant impact,” said Jonathan Stern, professor of medical statistics and epidemiology at the University of Bristol, in a statement. Sterne is Director of the NIHR Bristol Biomedical Research Center and Director of Health Data Research UK South West.

Similar to previous studies on blood clots, teams led by the Universities of Bristol, Cambridge, Edinburgh and Swansea found a ‘significantly increased’ risk of developing vascular disease in the first week or two after confirmation of COVID. I also discovered that 19, the risk decreased over time. However, unlike (risk of?) arterial thrombosis, which declined rapidly after the initial infection, the risk of VTE remained higher. found to remain elevated for longer periods in hospitalized patients.

Overall, the team found that within the first week of testing positive for COVID-19, patients were 21 times more likely to develop an arterial occlusive blood clot that could lead to a heart attack or stroke. discovered. This risk dropped to 1.3 times for him after 6 months. The increased risk of VTE went from 33-fold in his first week to 1.8-fold in his 27-49 weeks.

Although there was little association between COVID-19 and age-related blood clot risk, the researchers found that blacks and Asians, and people with a history of blood clots, were at higher risk compared to white patients. They found that patients with only mild or moderate cases of COVID-19 were also affected, but the excess risk was generally lower than for patients with severe infections.

“We showed that even those who weren’t hospitalized had a higher risk of blood clots in the first wave,” said Angela Wood, professor of biostatistics at Cambridge University and co-lead of the study.

“While the risk to individuals remains small, the public health impact could be substantial, making strategies to prevent vascular events critical to surviving the pandemic.”

The research team analyzed data using anonymized electronic medical records across the UK and Wales population from 1 January to 7 December 2020. history. The data collected predates large-scale vaccination campaigns and predominance of variants such as Delta and Omicron.

“The high number of COVID-19 infections in England and Wales in 2020 and 2021 may have significantly increased the burden of arterial thrombosis and VTE,” the authors of the paper wrote. It recommends preventive strategies such as physical examinations with care. Managing high-risk patients with doctors can help reduce the incidence of dangerous blood clots. With fewer patients seeing doctors, patients with chronic health problems have fewer regular check-ups, and they are no longer given prescriptions for medications to help lower blood pressure and cholesterol.

The researchers noted several limitations to the study, including the fact that patients who died of thrombosis-related events in nursing homes may not have been so documented, for example due to lack of diagnostic resources. Some people experiencing mild cases of blood clots may also avoid going to doctors and hospitals out of fear of contracting COVID-19. Data Collected also did not include information on specific low-grade thrombosis. Furthermore, the authors note that testing for COVID-19 was not widely available for mild or asymptomatic cases in the early days of the pandemic.

Looking ahead, researchers are studying data from 2020 and beyond to better understand how vaccinations and other variants affect vascular health.

COVID: Blood clot risk even higher one year after infection, study finds

Source link COVID: Blood clot risk even higher one year after infection, study finds

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